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June 22, 2024

The Conversation with Amanda de Cadenet

featuring
Lisa Mosconi

Welcome to The Conversation with Amanda de Cadenet. In today’s episode I speak with pioneering neuroscientist Dr. Lisa Mosconi, Associate Professor of Neuroscience in Neurology and Radiology and the director of the Alzheimer’s Prevention Program at Weill Cornell Medicine (WCM)/NewYork-Presbyterian Hospital. 

We discuss Dr. Mosconi's groundbreaking new research that sheds light on the intricate relationship between estrogen and the brain. Her work highlights the impact of estrogen on cognitive function and neurological health and opens new avenues for understanding how hormonal changes affect our minds as we age. 

Don’t miss Dr. Mosconi’s expertise on perimenopause, menopause, Alzheimer's, dementia, and the research and clinical trials she supervises. Join us as we explore her new study and discuss its implications for brain health, particularly for women.

Visit seed.com/amandac to apply the code 25AMANDAC for 25% off Seed’s VS-01™ and/or DS-01®. 

IN THIS EPISODE:

  • [0:34] Dr. Lisa Mosconi announces a new study that, for the first time, we can measure estrogen activity in the brain
  • [3:28] Discussion of why perimenopause and menopause are not topics of conversation  
  • [7:18] The upside of menopause and the definition that makes women feel they need to be fixed, the physiological reasons for menopause, and how the brain works
  • [14:50] Discussion of Alzheimer’s disease and the Alzheimer’s prevention program at Weill Cornell Medicine, New York/Presbyterian and taking the integrated medicine approach
  • [15:56] Discussion of why women seek Dr. Lisa’s advice to understand the chemical changes they are experiencing and the relief they find after FDA testing
  • [27:22] The misinformation around HRT and the various definitions of estrogen and who should and should not have hormone therapy
  • [42:07] Discussion of the next generation of hormones, women who choose not to do hormone therapy, hot flashes and ADHD
  • [45:01] Starting the ritual of the menopause party and the importance of having a brain baseline and how to contact Dr. Lisa if you are interested in a clinical trial 

KEY TAKEAWAYS:

  • When Lisa Mosconi learned that there was no way to measure estrogen activity in the brain, she spent five years developing medical science imaging to achieve an image of estrogen in the brain.
  • Women do not want to admit to perimenopause or menopause because it sends the signal that they are of a certain age, which makes them undesirable.
  • The brain is the hungriest organ in the body, requiring energy to support pregnancy, postpartum, and childbirth.

RESOURCES:

Dr. Lisa Mosconi - Book
Website www.lisamosconi.com
Dr. Lisa Mosconi’s Instagram
Dr. Lisa Mosconi’s Twitter/X

Books referenced: 

Discount on your Seed purchase:
Click this link seed.com/amandac to apply the code 25AMANDAC for 25% off Seed’s VS-01™ and/or DS-01®.

About This Podcast:
The Conversation with Amanda de Cadenet is a groundbreaking series of weekly interviews featuring candid conversations with impactful thought leaders. Host Amanda de Cadenet provides a platform for raw and honest discussions on a wide variety of topics, from porn to politics. Visit amandadecadenet.com to learn more and sign up for her newsletter. Follow Amanda on Instagram @amandadecadenet.

Biography:
Dr. Lisa Mosconi, PhD, is an Associate Professor of Neuroscience in Neurology and Radiology and director of the Alzheimer’s Prevention Program at Weill Cornell Medicine (WCM)/NewYork-Presbyterian Hospital. The program includes the NIH-funded Women’s Brain Initiative, the award-winning Alzheimer’s Prevention Clinic, and the newly launched Alzheimer’s Prevention Clinical Trials Unit. 

Dr. Mosconi holds a PhD in Neuroscience and Nuclear Medicine from the University of Florence, Italy. A world-renowned neuroscientist, she ranks in the top 1% of scientists of the past 20 years by official metrics. Recognized by The Times as one of the 17 most influential living female scientists and honored in ELLE 100: Women That Are Changing The World, Dr. Mosconi has been acclaimed as “the Mona Lisa of Neuroscience” by ELLE International. 

Dr. Mosconi’s NIH-funded research is focused on the early detection and prevention of cognitive aging and Alzheimer’s disease in at-risk individuals, especially women, using brain imaging techniques such as positron emission tomography and magnetic resonance imaging. Dr. Mosconi is passionately interested in how the risk of memory loss and dementia can be prevented through the combination of appropriate medical care and lifestyle modifications involving diet, physical, and intellectual fitness.

She is the author of the New York Times, USA Today, Canada’s #1 Health & Fitness, and The Sunday Times bestselling THE MENOPAUSE BRAIN (2024); of the New York Times, USA Today, Publishers Weekly, and Der Spiegel bestselling THE XX BRAIN (2020); and of the Amazon bestselling BRAIN FOOD (2018), which have been translated into more than 15 languages each. Dr. Mosconi’s popular TED talk “How menopause affects the brain” has been viewed over 4 million times since its release.